Development status and trend of pharmaceutical bli

2022-05-26
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Development status and trend of pharmaceutical blister packaging materials

with the rapid development of the packaging industry, people have very strict requirements for the plastic film used for pharmaceutical blister packaging: it should be thin and barrier enough, but also easy to tear but not easy to crack and high transparency. The drugs are clear at a glance and know what drugs gourd sells. Therefore, pharmaceutical companies are very careful in choosing the materials for blister packaging

at present, the most commonly used blister packaging materials for medicine are polyvinyl chloride (PVC) and polyvinylidene chloride (PVDC). The blister packaging adopts PVC, which has good compatibility, easy forming and sealing, and low price. However, it has poor thermal stability and low moisture barrier

as for PVDC film, it has the best barrier performance. It can be used under high temperature and high humidity conditions. Its performance is similar to that of PVC, but it is more widely used than PVC

development status of drug blister packaging in China

in China, there are more than 2000 drug packaging enterprises, which can produce 6 kinds and more than 30 varieties of drug packaging materials (including plastics), which can basically meet the needs of the domestic pharmaceutical industry, and the annual sales account for about 15% of the sales of the whole pharmaceutical industry

Chinese pharmaceutical manufacturers have applied for "production quality management practices" (GMP) to improve product quality? With the in-depth development of GMP transformation in pharmaceutical factories, some backward enterprises that do not meet the requirements of drug production quality, i.e. oxide skin production equipment with little significant preservation in the head, will be eliminated, and drug packaging will become more and more rigorous in material selection

Liang Wenbei, a pharmaceutical packaging market expert in the special film department of Honeywell International (Asia Pacific), said: "In the past, the packaging of Chinese drugs was casual, especially the moisture-proof technology was far lower than the international market level, so the damage rate of products was very high. With the increasing popularity of GMP in China, manufacturers pay more and more attention to the packaging materials of Chile sqm, the company with the largest output of lithium salt in the world, and plastics will have a lot of room for development in the drug market."

Shao Leiguang, business development manager of Honeywell special film department, added: "to successfully apply for GMP, manufacturers must meet many packaging safety requirements, which undoubtedly provides greater protection for consumers. In terms of material selection, different drugs choose different plastics, and the most commonly used are HDPE, PP, PVC and PE."

Liang Wenbei also said that China's current pharmaceutical packaging market is developing rapidly, with an annual growth rate of 14%. Many packaging have begun to be produced and processed in China, so the number of plastics exported for pharmaceutical packaging is becoming smaller and smaller. As for the world trend of drug packaging, the mainstream packaging with 100 capsules per bottle will gradually decline and replace it with blister packaging

PP

blister packaging, a new favorite of blister packaging materials, was launched in the early 1980s, and PVC and PVDC have always been the main materials of this kind of packaging. With the rapid development of packaging technology and pharmaceutical industry, some unsatisfactory shortcomings of PVC and PVDC continue to appear. For example, the water vapor barrier performance of PVC is poor, which is difficult to further meet higher production requirements, and the processing performance of PVDC is not ideal

in view of this, some plastic and pharmaceutical packaging manufacturers have developed blister packaging plastics that can supplement the above two properties. Generally, polypropylene (PP) within/0 is one of the materials favored by the market

PP is a partially crystalline plastic. In the production process of PP, after biaxial stretching, it will be in a high elastic state, and the lattice will be damaged during heating, resulting in obvious shrinkage of the film. In addition, the tensile degree of PP sheet is reduced to zero in the production process of the rolling process. Due to its small internal crystal, if combined with the quench technology, the adverse production situation that the plastic is in a high elastic state can be avoided

because PP has this characteristic, when it is selected as blister packaging material, it overcomes the shortcomings of PVC and PVDC. For example, PP molecule has no polarity, so it will not produce annoying situations such as adhesion between PVDC and metal production equipment, and its processing performance is far better than that of PVC and PVDC

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